Assessing resistance to new antibiotics

New Antibiotics—Resistance Is Futile

PLoS Biology | http://biology.plosjournals.org By next summer, more than 40% of Streptococcus pneumoniae strains in the United States will resist both penicillin and erythromycin, according to a recent prediction from the Harvard School of Public Health. The forecast, based on mathematical modeling, was published in the spring of 2003. It’s too early to tell whether that prediction is precisely...

Growing antibiotics resistance and the need for new antibiotics.

Growing antibiotic resistance is a global phenomenon in both developed and developing countries. Methicillin-resistant Staphylococcus aureus (MRSA) alone infects more than 94 000 people and kills nearly 19,000 in the US every year, more deaths than are caused by HIV/AIDS, Parkinson’s disease, emphysema, and homicide combined(1). Penicillin-resistant streptococcal pneumonia and vancomycin resist...

Phenotypic Resistance to Antibiotics

The development of antibiotic resistance is usually associated with genetic changes, either to the acquisition of resistance genes, or to mutations in elements relevant for the activity of the antibiotic. However, in some situations resistance can be achieved without any genetic alteration; this is called phenotypic resistance. Non-inherited resistance is associated to specific processes such a...

Resistance to antibiotics.

Propionibacterial resistance to antibiotics in patients with Acne Vulgaris

Background: Acne vulgaris is a self-limited disease that mainly involves the sebaceous follicles. Systemic antibiotic is a common therapeutic modality, so bacterial resistance can be a problem. Objectives: Assessment of Propionibacterium resistance to erythromycin, tetracycline, clindamycin and spiramycin. Patients and Methods: Sampling was done on lesions of 123 patients with acne vulgaris who...